One point separates Notts (21st) and Leyton Orient (23rd) going into Saturday's game at the Matchroom Stadium.
But Nolan, who had a spell as player-manager with the East London club last season, is giving the match no special treatment.
He said: "The result will not determine what's going to happen from now until the end of the season. We've got 15 games left and we've just got to make sure we win as many of them as possible.
"This is the next game and we want to win it - that's it. It doesn't matter that it's Leyton Orient or that I managed or played there. It has no bearing whatsoever - we've just got to go there and give a performance like we did on Tuesday and Saturday and we'll be OK."
The manager says Thierry Audel is doubtful for the weekend's match after picking up a groin injury in the midweek draw against Exeter City.
And, when asked about the depth of his squad, he reserved special praise for a man who didn't make his matchday squad for that match.
Nolan said: "I've got the likes of Haydn Hollis, who was in my team or on the bench a couple of weeks ago, having to sit in the stands because we've got strength in depth all over.
"But I must say his attitude towards everything he does is absolutely first class. If it ever hurts me leaving someone out as much as him, I'll be very surprised.
"Everything about him is just unbelievable and, if someone drops out over the next couple of days, he'll probably be the one to get back on the bench or in the team, just because of everything he does around the place."