A Ryan Bowman hat-trick knocked us out of the Emirates FA Cup at the second-round stage.
Richard Brindley had equalised for us in the first half before 17-year-old James Sanderson made it 3-2 on his debut.
But it was to be nothing more than a consolation as we exited the competition.
With only a two-day gap following a tough double-header against AFC Wimbledon and Crawley, Luke Williams heavily rotated his side on a freezing night at Meadow Lane.
Aidan Stone started between the sticks and was shielded by Connell Rawlinson, Aden Baldwin and Richard Brindley.
Adam Chicksen and Will Randall were deployed out wide, while Dan Gosling was handed his first start for the club in a fluid midfield which also contained stand-in skipper John Bostock, Aaron Nemane and Sam Austin.
Having scored his first league goal for the club in midweek, Junior Morias took Macaulay Langstaff’s spot up top – with the prolific number nine having to settle for a place on the bench alongside the likes of Kyle Cameron, Jodi Jones, Tobi Adebayo, Ollie Tipton and Lewis Macari.
It was also to be a memorable night for Sanderson who, the day after celebrating his 17th birthday, made the bench alongside fellow youngsters Luther Munakandafa and Charlie Gill.
We were to have the nightmare start, though, as Baldwin’s slip on the byline gifted possession to the visitors, who easily worked the ball to Bowman for a close-range finish past the helpless Stone with only a minute on the clock.
A composed and controlled first half was to follow, however, although a well-organised Shrewsbury side were keeping us at bay.
That was until Brindley, who had seen a sighter blocked shortly before, collected the ball in space 25 yards out and struck the ball sweetly into the far corner.
Shrewsbury had offered very little threat other than their goal but could have gone back ahead in the first of two added minutes at the end of the first half, Baldwin making an excellent last-ditch challenge to deny Jordan Shipley after his run had broken our defensive line.
But, after we’d emerged for the second half unchanged, we gifted Bowman his second goal of the game when, after Randall had hooked the ball into his own area, Rawlinson’s attempted header back towards him allowed the forward to control and finish six yards out.
Randall sought to atone for his part in the goal with a promising run into the area shortly afterwards, which resulted in him sending a well-struck shot narrowly over.
But the game was all but over moments later as a comfortable-looking pass-back for Brindley led to him being caught in possession, with Baldwin also failing to deal with the danger – allowing Bowman to carry the ball into the area and finish past Stone.
Jones and Langstaff entered the fray and were followed by Tipton and Sanderson with 73 minutes on the clock.
And, two minutes later, the debutant dragged us back into the contest with an excellent low finish following excellent hold-up play in the area by Morias.
We had our visitors penned in, as we had for such large swathes of the game, and came agonisingly close to an equaliser as Morias' brilliantly-executed overhead kick flashed just wide of the post following good work from the superb Austin.
But that would be the closest we’d come on a night when the concession of three cheap goals cost us our place in the third-round draw.
STARTING XI: Stone; Rawlinson (Langstaff 64'), Baldwin, Brindley (Tipton 73'); Chicksen, Randall (Jones 64'); Gosling (Sanderson 72'), Austin, Bostock, Nemane; Morias
SUBS: Cameron, Macari, Adebayo, Munakandafa, Gill
BOOKINGS: Bostock 72'
ATTENDANCE: 4,551 (674)